Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of allelic heterogeneity at type-2 diabetes loci and impact on prediction.

PloS one - 1 Jan 2014

Klimentidis Yann C, Zhou Jin, Wineinger Nathan E

Abstract excerpt

Although over 60 single nucleotide polymorphisms (SNPs) have been identified by meta-analysis of genome-wide association studies for type-2 diabetes (T2D) among individuals of European descent, much of the genetic variation remains unexplained. There are likely many more SNPs that contribute to variation in T2D risk, some of which may lie in the regions surrounding established SNPs--a phenomenon often referred to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Databases, Genetic
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Predictive Value of Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 25393876
DOI: 10.1371/journal.pone.0113072
PMCID: PMC4231111

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of allelic heterogeneity at type-2 diabetes loci and impact on prediction.PMID 25393876Read ↗

Genetic markers of type 2 diabetes: Progress in genome-wide association studies and clinical application for risk prediction.Semantic proximity Read ↗

Recent advances in understanding the genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Genetics of Type 2 Diabetes: Implications from Large-Scale Studies.Semantic proximity Read ↗

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.Semantic proximity Read ↗

Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.Semantic proximity Read ↗

Genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Stratified genome-wide association analysis of type 2 diabetes reveals subgroups with genetic and environmental heterogeneity.Semantic proximity Read ↗

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.Semantic proximity Read ↗

Genomic risk score provides predictive performance for type 2 diabetes in the UK biobank.Semantic proximity Read ↗

Cross-sectional and longitudinal replication analyses of genome-wide association loci of type 2 diabetes in Han Chinese.Semantic proximity Read ↗

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome mapsSemantic proximity Read ↗

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.