Article
[Effects of Rad9 mutants with impaired DNA mismatch repair function on tumorigenesis of colorectal cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 May 2016
Kong M, An L L, Hu Z S, Li K M, Zhao Y, Cai Z Y, Sun J Y, Wang H F, Zhang S C, Zhang Z Y
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the effects of Rad9 mutants with impaired DNA mismatch repair (MMR) function on the tumorigenesis of colorectal cancer. METHODS: The colorectal cancer tumor samples were collected from 100 patients. The mutation profiles of human Rad9 (hRad9) gene in these samples were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) and sequencing. The...
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