Article
[Mismatch repair protein].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Sept 1997
Ikejima M, Shimada T
Abstract excerpt
A DNA mismatch repair system exists that repairs mispaired bases formed during DNA replication and genetic recombination. Genetic defects in this mismatch repair system are known to increase the rate of spontaneous mutation in Escherichia coli. Some cases of inherited cancer are associated with inherited defects of mismatch repair genes, showing the importance of the mismatch repair system in maintenance of...
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