Article
[Relation between mismatch repair genes and colon cancer].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Feb 2014
Ma Junli, Zeng Shan
Abstract excerpt
Mismatch repair (MMR) system is one form of DNA repair mechanisms, which plays an important role in rectifying the mismatch of base pairs, reducing gene mutations and keeping genome stability. Abnormal expression of MMR regulated by miRNA is closely related to the development of colon cancer. Functional defects of MMR (dMMR) with particular clinical characteristics can be used as a potential prognostic and...
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