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Article

Determinants of Sir2-Mediated, Silent Chromatin Cohesion.

Molecular and cellular biology - 1 Aug 2016

Chen Yu-Fan, Chou Chia-Ching, Gartenberg Marc R

Abstract excerpt

Cohesin associates with distinct sites on chromosomes to mediate sister chromatid cohesion. Single cohesin complexes are thought to bind by encircling both sister chromatids in a topological embrace. Transcriptionally repressed chromosomal domains in the yeast Saccharomyces cerevisiae represent specialized sites of cohesion where cohesin binds silent chromatin in a Sir2-dependent fashion. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27185881
DOI: 10.1128/MCB.00057-16
PMCID: PMC4946433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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