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Article

GM-CSF Mediates Mesenchymal–Epithelial Cross-talk in Pancreatic Cancer

16 May 2016

Abstract excerpt

UNLABELLED: Pancreatic ductal adenocarcinoma (PDA) is characterized by a dense stroma consisting of a prevalence of activated fibroblasts whose functional contributions to pancreatic tumorigenesis remain incompletely understood. In this study, we provide the first identification and characterization of mesenchymal stem cells (MSC) within the human PDA microenvironment, highlighting the heterogeneity of the...

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PMID: 27184426
DOI: 10.1158/2159-8290.cd-15-0947

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