HCV-related liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2.

doi:10.18632/oncotarget.9303

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Article

HCV-related liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2.

Oncotarget - 21 Jun 2016

De Re Valli, De Zorzi Mariangela, Caggiari Laura, Lauletta Gianfranco, Tornesello Maria Lina, Fognani Elisa, Miorin Marta, Racanelli Vito, Quartuccio Luca, Gragnani Laura, Russi Sabino, Pavone Fabio, Ghersetti Michela, Costa Elena Garlatti, Casarin Pietro, Bomben Riccardo, Mazzaro Cesare, Basaglia Giancarlo, Berretta Massimiliano, Vaccher Emanuela, Izzo Francesco, Buonaguro Franco Maria, De Vita Salvatore, Zignego Anna Linda, De Paoli Paolo, Dolcetti Riccardo

Abstract excerpt

To explore the relationship between innate immunity and hepatitis C Virus (HCV) in determining the risk of cirrhosis (CIR), hepatocellular carcinoma (HCC), mixed cryoglobulinemia syndrome (MCS) and non-Hodgkin lymphoma (NHL), we investigated the impact of the toll-like receptor-2 (TLR2) and interleukin-28B (IL28B) genetic variants. TLR2 -174 del variant was associated with TLR2 expression and with specific...

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PMID: 27183918
DOI: 10.18632/oncotarget.9303
PMCID: PMC5122326

Genes

TLR2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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