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IL28B, TLR7 SNPs, and cytomegalovirus infection are risk factors for advanced liver disease in chronic hepatitis C patients.

Expert review of anti-infective therapy - 1 Jan 2022

Khalil Fatma Omar, Alsebaey Ayman, Kasemy Zeinab Abdelaziz, Abdelmageed Sabry Moawad, Bedair Hanan Mosaad, Abdelsattar Shimaa

Abstract excerpt

BACKGROUND: Chronic hepatitis C (CHC) is a leading cause of cirrhosis and hepatocellular carcinoma (HCC). This study aimed to study the association of IL28B, toll-like receptor (TLR) 7, cytomegalovirus and advanced liver disease. METHODS: Four groups were included; control (n = 125, 25.9%), CHC (n = 114, 23.6%), liver cirrhosis (n = 120, 24.8%), and HCC (n = 124, 25.7%). RESULTS: In CHC group, patients were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34047252
DOI: 10.1080/14787210.2021.1935239

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