Article
Screening for circulating RAS/RAF mutations by multiplex digital PCR.
Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2016
Andersen Rikke Fredslund, Jakobsen Anders
Abstract excerpt
Recent years have shown a large interest in the application of liquid biopsies in cancer management. Circulating tumor DNA (ctDNA) has been investigated for potential use in treatment selection, monitoring of treatment response, and early detection of recurrence. Advances have been hampered by technical challenges primarily due to the low levels of ctDNA in patients with localized disease and in patients...
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