Article
Identification of mutant K-RAS in pituitary macroadenoma.
Pituitary - 1 Oct 2021
Aran Veronica, Heringer Manoela, da Mata Paulo Jose, Kasuki Leandro, Miranda Renan Lyra, Andreiuolo Felipe, Chimelli Leila, Filho Paulo Niemeyer, Gadelha Monica Roberto, Neto Vivaldo Moura
Abstract excerpt
PURPOSE: RAS genes are among the most frequently mutated genes in cancer, where their mutation frequency varies according to the distinct RAS isoforms and tumour types. Despite occurring more prevalent in malignant tumours, RAS mutations were also observed in few benign tumours. Pituitary adenomas are examples of benign tumours which vary in size and aggressiveness. The present study was performed to investigate,...
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