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Article

Electrostatic networks control plug stabilization in the PapC usher.

Molecular membrane biology - 1 Jan 2000

Pham Thieng, Henderson Nadine S, Werneburg Glenn T, Thanassi David G, Delcour Anne H

Abstract excerpt

The PapC usher, a β-barrel pore in the outer membrane of uropathogenic Escherichia coli, is used for assembly of the P pilus, a key virulence factor in bacterial colonization of human kidney cells. Each PapC protein is composed of a 24-stranded β-barrel channel, flanked by N- and C-terminal globular domains protruding into the periplasm, and occluded by a plug domain (PD). The PD is displaced from the channel...

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Identifiers

PMID: 27181766
DOI: 10.3109/09687688.2016.1160450
PMCID: PMC4962327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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