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Article

Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus.

Scientific reports - 16 May 2016

Sakiyama Masayuki, Matsuo Hirotaka, Nakaoka Hirofumi, Yamamoto Ken, Nakayama Akiyoshi, Nakamura Takahiro, Kawai Sayo, Okada Rieko, Ooyama Hiroshi, Shimizu Toru, Shinomiya Nariyoshi

Abstract excerpt

Gout is a common disease resulting from hyperuricemia. Recently, a genome-wide association study identified an association between gout and a single nucleotide polymorphism (SNP) rs2188380, located on an intergenic region between MYL2 and CUX2 on chromosome 12. However, other genes around rs2188380 could possibly be gout susceptibility genes. Therefore, we performed a fine-mapping study of the MYL2-CUX2 region....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Chromosome Mapping
Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Genotyping Techniques
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Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27181629
DOI: 10.1038/srep25360
PMCID: PMC4867610

Genes

CUX2
MYL2
ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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