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Associations of the ALDH2 rs671 polymorphism and alcohol intake with early-onset gout in a Chinese male cohort.

Joint bone spine - 1 Jul 2025

Hu Shuhui, Dalbeth Nicola, Li Zhiqiang, Chen Ying, Dong Bingzi, Wang Can, Sun Wenyan, Li Changgui, Lu Jie

Abstract excerpt

OBJECTIVE: Gout in young people is increasingly common across the world, including in China. This study aimed to identify clinical and genetic associations with early-onset gout in Chinese men. METHODS: One thousand two hundred and one Chinese men with gout were included. Early-onset gout was defined as the first presentation of gout at <30years. Twenty single nucleotide polymorphisms (SNPs) identified as...

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Source

Identifiers

PMID: 40015360
DOI: 10.1016/j.jbspin.2025.105876

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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