Article
Functional variants of the pentraxin 3 gene are associated with the metastasis and progression of prostate cancer.
Journal of cellular and molecular medicine - 1 Aug 2024
Weng Wei-Chun, Hsieh Yi-Hsien, Lin Chia-Yen, Liu Yu-Fan, Su Shih-Chi, Wang Shian-Shiang, Yang Shun-Fa
Abstract excerpt
Age, ethnic background and genetic components have been identified as the established risks for prostate cancer (PCa). Pentraxin 3 (PTX3), originally identified as a pattern-recognition molecule for defence against infectious agents, has multiple functions in tissue repair and in the regulation of cancer-associated inflammation. In this study, we sought to investigate the impact of PTX3 gene variants on the...
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