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Article

The Impact of Pentraxin 3 on Crohn's Disease Phenotype.

International journal of molecular sciences - 27 Oct 2024

Kofla-Dlubacz Anna, Pawlik-Sobecka Lilla, Pytrus Tomasz, Borys-Iwanicka Agnieszka, Gorka-Dynysiewicz Joanna

Abstract excerpt

Pentraxin 3 [PTX3] is an acute-phase protein playing an important role in the regulation of the humoral arm of immune response. As one of the molecules from the conservative family of pentraxins, PTX3 is a soluble mediator involved in the transduction of pro-inflammatory signals between immunocompetent cells. Additionally, recognizing damage-associated molecular patterns (DAMPs) during tissue injury mediates...

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Identifiers

PMID: 39519095
DOI: 10.3390/ijms252111544
PMCID: PMC11546887

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