Article
Usefulness of Integrase resistance testing in proviral HIV-1 DNA in patients with Raltegravir prior failure.
BMC infectious diseases - 13 May 2016
Fernández-Caballero Jose Ángel, Chueca Natalia, Álvarez Marta, Mérida María Dolores, López Josefa, Sánchez José Antonio, Vinuesa David, Martínez María Ángeles, Hernández José, García Federico
Abstract excerpt
BACKGROUND: In our study, we have hypothesized that proviral DNA may show the history of mutations that emerged at previous failures to a Raltegravir containing regimen, in patients who are currently undetectable and candidates to simplification to a Dolutegravir containing regimen, in order to decide on once a day or twice a day dosing. METHODS: We have performed a pilot, observational, retrospective, non...
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