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Article

Evaluation of integrase resistance in individuals who failed a regimen containing dolutegravir in French and Italian clinical settings.

The Journal of antimicrobial chemotherapy - 1 Jun 2023

Armenia Daniele, Santoro Maria M, Charpentier Charlotte, Bertoli Ada, Forbici Federica, Calvez Vincent, Descamps Diane, Ceccherini-Silberstein Francesca, Marcelin Anne-Genevieve, Flandre Philippe

Abstract excerpt

BACKGROUND: This work aims to evaluate integrase resistance and its predictors in HIV-1 infected combined antiretroviral therapy (cART) experienced individuals failing a dolutegravir-based regimen. METHODS: Major resistance mutations (MRM) and genotypic susceptibility score (GSS) of dolutegravir companion drugs were evaluated on plasma genotypic resistance test (GRT) performed at dolutegravir failure. Logistic...

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Identifiers

PMID: 37258034
DOI: 10.1093/jac/dkad101

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