Article
Hypomethylation of FAM63B in bipolar disorder patients.
Clinical epigenetics - 1 Jan 2016
Starnawska Anna, Demontis Ditte, McQuillin Andrew, O'Brien Niamh L, Staunstrup Nicklas H, Mors Ole, Nielsen Anders L, Børglum Anders D, Nyegaard Mette
Abstract excerpt
Bipolar disorder (BD) and schizophrenia (SZ) are known to share common genetic and psychosocial risk factors. A recent epigenome-wide association study performed on blood samples from SZ patients found significant hypomethylation of FAM63B in exon 9. Here, we used iPLEX-based methylation analysis to investigate two CpG sites in FAM63B in blood samples from 459 BD cases and 268 controls. Both sites were...
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