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Article

Drosophila maelstrom ensures proper germline stem cell lineage differentiation by repressing microRNA-7.

Developmental cell - 1 Sept 2009

Pek Jun Wei, Lim Ai Khim, Kai Toshie

Abstract excerpt

Nuage is a germline-unique perinuclear structure conserved throughout the animal kingdom. Maelstrom (Mael) is an unusual nuage component, as it is also found in the nucleus. Mael contains a High Mobility Group box, known to mediate DNA binding. We show that Mael nuclear function is required for proper differentiation in the Drosophila germline stem cell (GSC) lineage. In mael mutant testes, transit-amplifying...

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Identifiers

PMID: 19758565
DOI: 10.1016/j.devcel.2009.07.017

Genes

GSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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