Article
Frequency of TLR4 (1063A/G and 1363C/T) polymorphisms in healthy and HIV-infected Omani individuals and their relationship to viral load and T cell count.
Genetics and molecular research : GMR - 4 Apr 2016
Said E A, Al-Yafei F, Zadjali F, Al-Balushi M S, Hasson S S, Al-Mahroqi S H, Koh C Y, Al-Naamani K, Al-Busaidi J Z, Idris M A, Balkhair A, Al-Jabri A A
Abstract excerpt
Toll-like receptors (TLRs) are essential elements of the innate immune response to different infections including the infection with human immunodeficiency virus (HIV). Single nucleotide polymorphisms (SNPs) in TLRs such as TLR4 1063A/G and 1363C/T have been found to be associated with changes in CD4 count, viral load (VL), and disease progression during HIV infection. However, the association of these SNPs with...
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