Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals.

AIDS (London, England) - 27 Nov 2009

Pine Samuel O, McElrath M Juliana, Bochud Pierre-Yves

Abstract excerpt

OBJECTIVES: Toll-like receptors (TLRs) are innate immune sensors that are integral to resisting chronic and opportunistic infections. Mounting evidence implicates TLR polymorphisms in susceptibilities to various infectious diseases, including HIV-1. We investigated the impact of TLR single nucleotide polymorphisms (SNPs) on clinical outcome in a seroincident cohort of HIV-1-infected volunteers. DESIGN: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Lymphocyte Count
Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Toll-Like Receptor 2

Share to Toll-Like Receptor 3

Share to Toll-Like Receptor 4

Share to Toll-Like Receptor 9

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 19855253
DOI: 10.1097/QAD.0b013e328330b489
PMCID: PMC2919356

Genes

TLR4
TLR9
TLR2
TLR3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals.PMID 19855253Read ↗

Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection.Semantic proximity Read ↗

Toll-like receptor polymorphism associations with HIV-1 outcomes among sub-Saharan Africans.Semantic proximity Read ↗

A frequent functional toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression.Semantic proximity Read ↗

Influence of the Toll-like receptor 9 1635A/G polymorphism on the CD4 count, HIV viral load, and clinical progression.Semantic proximity Read ↗

A functional toll-like receptor 8 variant is associated with HIV disease restriction.Semantic proximity Read ↗

Influence of genetic variability in toll-like receptors (TLR 2, TLR 4, and TLR 9) on human immunodeficiency virus-1 disease progression.Semantic proximity Read ↗

Association of toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms with increased infection risk in patients with advanced HIV-1 infection.Semantic proximity Read ↗

Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy–Naive Participants From the Strategic Timing of AntiRetroviral Treatment TrialSemantic proximity Read ↗

Interaction of the Host and Viral Genome and Their Influence on HIV DiseaseSemantic proximity Read ↗

Association of toll-like receptor polymorphisms with acquisition of HIV infection and clinical findings: A protocol for systematic review and meta-analysis.Semantic proximity Read ↗

Strong Association of the rs4986790 Single Nucleotide Polymorphism (SNP) of the Toll-Like Receptor 4 (TLR4) Gene with Human Immunodeficiency Virus (HIV) Infection: A Meta-Analysis.Semantic proximity Read ↗

An assessment of toll-like receptor 7 and 8 gene polymorphisms with susceptibility to HIV-1 infection, AIDS development and response to antiretroviral therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.