Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Polymorphisms of TGFB1, TGFBR1, SNAI1 and TWIST1 Are Associated with Endometrial Cancer Susceptibility in Chinese Han Women.

PloS one - 1 Jan 2016

Yang Li, Wang Ya-Jun, Zheng Li-Yuan, Jia Yu-Mian, Chen Yi-Lin, Chen Lan, Liu Dong-Ge, Li Xiang-Hong, Guo Hong-Yan, Sun Ying-Li, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

Endometrial cancer (EC) is a complex disease involving multiple gene-gene and gene-environment interactions. TGF-β signaling plays pivotal roles in EC development. This study aimed to investigate whether the genetic polymorphisms of TGF-β signaling related genes TGFB1, TGFBR1, SNAI1 and TWIST1 contribute to EC susceptibility. Using the TaqMan Genotyping Assay, 19 tagging-SNPs of these four genes were genotyped in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometrial Neoplasms
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactor Dimensionality Reduction

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptors, Transforming Growth Factor beta

Share to Snail Family Transcription Factors

Share to Transforming Growth Factor beta1

Share to Twist-Related Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 27171242
DOI: 10.1371/journal.pone.0155270
PMCID: PMC4865208

Genes

TGFBR1
TGFB1
TWIST1
SNAI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Polymorphisms of TGFB1, TGFBR1, SNAI1 and TWIST1 Are Associated with Endometrial Cancer Susceptibility in Chinese Han Women.PMID 27171242Read ↗

Association between TGFBR1 polymorphisms and cancer risk: a meta-analysis of 35 case-control studies.Semantic proximity Read ↗

Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population.Semantic proximity Read ↗

TGFBR1 tagging SNPs and gastric cancer susceptibility: a two-stage case-control study in Chinese population.Semantic proximity Read ↗

Genetic variants in TGF-β pathway are associated with ovarian cancer risk.Semantic proximity Read ↗

Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians.Semantic proximity Read ↗

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.Semantic proximity Read ↗

TGF-β signaling pathway and breast cancer susceptibility.Semantic proximity Read ↗

Association study of TGFBR2 and miR-518 gene polymorphisms with age at natural menopause, premature ovarian failure, and early menopause among Chinese Han women.Semantic proximity Read ↗

BET1L and TNRC6B associate with uterine fibroid risk among European Americans.Semantic proximity Read ↗

Transforming growth factor beta 1 (TGFβ1) polymorphisms and haplotype structures have dual roles in breast cancer pathogenesis.Semantic proximity Read ↗

Association between the TGFBR2 G-875A polymorphism and cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

Association of BET1L and TNRC6B with uterine leiomyoma risk and its relevant clinical features in Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.