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Article

ABCC3 as a marker for multidrug resistance in non-small cell lung cancer

1 Nov 2013

Abstract excerpt

Multidrug resistance (MDR) contributes to the failure of chemotherapy and high mortality in non-small cell lung cancer (NSCLC). We aim to identify MDR genes that predict tumor response to chemotherapy. 199 NSCLC fresh tissue samples were tested for chemosensitivity by MTT assay. cDNA microarray was done with 5 samples with highest resistance and 6 samples with highest sensitivity. Expression of ABCC3 mRNA and...

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PMID: 24176985
DOI: 10.1038/srep03120

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