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Article

The putative U94 integrase is dispensable for human herpesvirus 6 (HHV-6) chromosomal integration

11 May 2016

Abstract excerpt

Human herpesvirus 6 (HHV-6) can integrate its genome into the telomeres of host chromosomes and is present in the germline of about 1 % of the human population. HHV-6 encodes a putative integrase U94 that possesses all molecular functions required for recombination including DNA-binding, ATPase, helicase and nuclease activity, and was hypothesized by many researchers to facilitate integration ever since the...

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PMID: 27170009
DOI: 10.1099/jgv.0.000502

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