Article

Endogenization and excision of human herpesvirus 6 in human genomes

2019-12-26

Abstract excerpt

<h4>ABSTRACT</h4> The genome of human herpesvirus 6 (HHV-6) is integrated within the nuclear genome of about 1% of humans, but how this came about is not clear. HHV-6 integrates into telomeres, and this has recently been associated with polymorphisms affecting MOV10L1 . MOV10L1 is located on the subtelomere of chromosome 22q (chr22q) and is required to make PIWI-interacting RNAs (piRNAs). piRNAs block integrati...

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Literature Corpus work: 028d231b-0e1e-51d1-bc21-8f205328fda0
DOI: 10.1101/2019.12.19.882522

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