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Inherited chromosomally integrated human herpesvirus 6 genomes are ancient, intact and potentially able to reactivate from telomeres

2017-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Human herpesviruses 6A and 6B (HHV6-A and HHV-6B; species Human herpesvirus 6A and Human herpesvirus 6B ) have the capacity to integrate into telomeres, the essential capping structures of chromosomes that play roles in cancer and ageing. About 1% of people worldwide are carriers of chromosomally integrated HHV-6 (ciHHV-6), which is inherited as a genetic trait. Understanding the consequences...

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Literature Corpus work
1dda9ba2-f2b9-57cf-b4ad-983eb18d055d
DOI
10.1101/166041
Open publication

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Inherited chromosomally integrated human herpesvirus 6 genomes are ancient, intact and potentially able to reactivate from telomeresDOI 10.1101/166041
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