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Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration

4 May 2017

Abstract excerpt

ABSTRACT Human herpesviruses 6A/B (HHV-6A/B) can integrate their viral genomes in the telomeres of human chromosomes. The viral and cellular factors contributing to HHV-6A/B integration remain largely unknown, mostly due to the lack of efficient and reproducible cell culture models to study HHV-6A/B integration. In this study, we characterized the HHV-6A/B integration efficiencies in several human cell lines...

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PMID: 28468878
DOI: 10.1128/jvi.00437-17

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