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Latency, Integration, and Reactivation of Human Herpesvirus-6

24 Jul 2017

Abstract excerpt

Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into the host telomeres, rather than by episome formation. In about 1% of the human population, human herpes virus-6 (HHV-6) integration into germline cells allows...

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PMID: 28737715
DOI: 10.3390/v9070194

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