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Article

Quantitative Mass Spectrometry Reveals Changes in Histone H2B Variants as Cells Undergo Inorganic Arsenic-Mediated Cellular Transformation.

Molecular & cellular proteomics : MCP - 1 Jul 2016

Rea Matthew, Jiang Tingting, Eleazer Rebekah, Eckstein Meredith, Marshall Alan G, Fondufe-Mittendorf Yvonne N

Abstract excerpt

Exposure to inorganic arsenic, a ubiquitous environmental toxic metalloid, leads to carcinogenesis. However, the mechanism is unknown. Several studies have shown that inorganic arsenic exposure alters specific gene expression patterns, possibly through alterations in chromatin structure. While most studies on understanding the mechanism of chromatin-mediated gene regulation have focused on histone...

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Identifiers

PMID: 27169413
DOI: 10.1074/mcp.M116.058412
PMCID: PMC4937513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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