Article
Arsenic-induced sumoylation of Mus81 is involved in regulating genomic stability.
Cell cycle (Georgetown, Tex.) - 18 Apr 2017
Hu Liyan, Yang Feikun, Lu Lou, Dai Wei
Abstract excerpt
Chronic environmental exposure to metal toxicants such as chromium and arsenic is closely related to the development of several types of common cancers. Genetic and epigenetic studies in the past decade reveal that post-translational modifications of histones play a role in metal carcinogenesis. However, exact molecular mechanisms of metal carcinogenesis remain to be elucidated. In this study we found that As2O3,...
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