Article
Interleukin (IL)-23 Receptor, IL-17A and IL-17F Gene Polymorphisms in Brazilian Patients with Rheumatoid Arthritis.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2017
Gomes da Silva Isaura Isabelle Fonseca, Angelo Hildson Dornelas, Rushansky Eliezer, Mariano Maria Helena, Maia Maria de Mascena Diniz, de Souza Paulo Roberto Eleuterio
Abstract excerpt
Rheumatoid arthritis (RA) is a progressive, autoimmune disease for which the previous studies have shown that some functional polymorphisms can influence its etiology. Knowing this, the aim of this study was to investigate the association of +2199 A/C IL-23R (rs10889677), -197 G/A IL-17A (rs22759...
Topics
- Adult
- Aged, 80 and over
- Arthritis, Rheumatoid
- Brazil
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-17
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Receptors, Interleukin
- Th17 Cells
- Young Adult