Association of IL17A and IL17F genes with rheumatoid arthritis disease and the impact of genetic polymorphisms on response to treatment.

doi:10.1016/j.imlet.2017.01.013

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Article

Association of IL17A and IL17F genes with rheumatoid arthritis disease and the impact of genetic polymorphisms on response to treatment.

Immunology letters - 1 Mar 2017

Marwa Ouled Salah, Kalthoum Tizaoui, Wajih Kaabachi, Kamel Hamzaoui

Abstract excerpt

BACKGROUND: Previous studies have reported an association between polymorphisms in Il17A and IL17F genes and the prevalence of rheumatoid arthritis (RA) in Caucasian populations. The aim of the current study was to investigate that polymorphisms in both genes may affect RA susceptibility in the T...

Topics

Adult
Alleles
Antirheumatic Agents
Arthritis, Rheumatoid
Biomarkers
Case-Control Studies
Enzyme-Linked Immunosorbent Assay
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-17
Male
Methotrexate
Middle Aged
Odds Ratio

Source

Open in PubMed

Identifiers

PMID: 28143790
DOI: 10.1016/j.imlet.2017.01.013

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-28143790-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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