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Article

Targeting the lncRNA SAMMSON Reveals Metabolic Vulnerability in Melanoma.

Cancer cell - 9 May 2016

Goding Colin R

Abstract excerpt

In a recent study, Leucci et al. report a role for the long non-coding RNA SAMMSON in driving mitochondrial function in melanoma. Targeting SAMMSON, the gene of which is frequently co-amplified with MITF, highlights a new cell-type-specific therapeutic vulnerability in melanoma irrespective of BRAF, NRAS, or p53 status.

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Topics

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Share to BRAF gene
Share to MITF gene
Share to NRAS gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Melanoma

Share to Mitochondria

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Share to Proto-Oncogene Proteins B-raf

Share to RNA, Long Noncoding

Source

Identifiers

PMID: 27165740
DOI: 10.1016/j.ccell.2016.04.010

Genes

BRAF
MITF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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