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The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival

10 Sept 2021

Abstract excerpt

Long non-coding RNAs (lncRNAs) can exhibit cell-type and cancer-type specific expression profiles, making them highly attractive as therapeutic targets. Pan-cancer RNA sequencing data revealed broad expression of the SAMMSON lncRNA in uveal melanoma (UM), the most common primary intraocular malignancy in adults. Currently, there are no effective treatments for UM patients with metastatic disease, resulting in a...

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PMID: 34508176
DOI: 10.1038/s41388-021-02006-x

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