Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mesangial immune complex glomerulonephritis due to complement factor D deficiency.

Kidney international - 1 Jun 2007

Abrera-Abeleda M A, Xu Y, Pickering M C, Smith R J H, Sethi S

Abstract excerpt

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Capillaries
Share to Complement C3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescein-5-isothiocyanate

Share to Glomerular Mesangium

Share to Glomerulonephritis

Share to Histocytochemistry

Share to Kidney Glomerulus

Source

Identifiers

PMID: 17410102
DOI: 10.1038/sj.ki.5002235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17410102-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mesangial immune complex glomerulonephritis due to complement factor D deficiency.PMID 17410102Read ↗

Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.Semantic proximity Read ↗

Complement factor H and the hemolytic uremic syndromeSemantic proximity Read ↗

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H.Semantic proximity Read ↗

Characterization of a Factor H Mutation That Perturbs the Alternative Pathway of Complement in a Family with Membranoproliferative GNSemantic proximity Read ↗

C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complementSemantic proximity Read ↗

Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domainsSemantic proximity Read ↗

Membranoproliferative glomerulonephritis with C3NeF and genetic complement dysregulation.Semantic proximity Read ↗

The classical pathway triggers pathogenic complement activation in membranous nephropathySemantic proximity Read ↗

The role of complement iC3b in dense deposit diseaseSemantic proximity Read ↗

Current Understanding of the Role of Complement in IgA Nephropathy.Semantic proximity Read ↗

Effects of complement factor D deficiency on the renal disease of MRL/lpr miceSemantic proximity Read ↗

C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.