Article
Association of androgen metabolism gene polymorphisms with prostate cancer risk and androgen concentrations: Results from the Prostate Cancer Prevention Trial.
Cancer - 1 Aug 2016
Price Douglas K, Chau Cindy H, Till Cathee, Goodman Phyllis J, Leach Robin J, Johnson-Pais Teresa L, Hsing Ann W, Hoque Ashraful, Parnes Howard L, Schenk Jeannette M, Tangen Catherine M, Thompson Ian M, Reichardt Juergen K V, Figg William D
Abstract excerpt
BACKGROUND: Prostate cancer is highly influenced by androgens and genes. The authors investigated whether genetic polymorphisms along the androgen biosynthesis and metabolism pathways are associated with androgen concentrations or with the risk of prostate cancer or high-grade disease from finasteride treatment. METHODS: A nested case-control study from the Prostate Cancer Prevention Trial using data from men who...
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