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Article

Finasteride concentrations and prostate cancer risk: results from the Prostate Cancer Prevention Trial.

PloS one - 1 Jan 2015

Chau Cindy H, Price Douglas K, Till Cathee, Goodman Phyllis J, Chen Xiaohong, Leach Robin J, Johnson-Pais Teresa L, Hsing Ann W, Hoque Ashraful, Tangen Catherine M, Chu Lisa, Parnes Howard L, Schenk Jeannette M, Reichardt Juergen K V, Thompson Ian M, Figg William D

Abstract excerpt

OBJECTIVE: In the Prostate Cancer Prevention Trial (PCPT), finasteride reduced the risk of prostate cancer by 25%, even though high-grade prostate cancer was more common in the finasteride group. However, it remains to be determined whether finasteride concentrations may affect prostate cancer risk. In this study, we examined the association between serum finasteride concentrations and the risk of prostate cancer...

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Identifiers

PMID: 25955319
DOI: 10.1371/journal.pone.0126672
PMCID: PMC4425512

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