Article
Association Between Combined Presence of Hepatitis C Virus and Polymorphisms in Different Genes With Toxicities of Methotrexate and 6-Mercaptopurine in Children With Acute Lymphoblastic Leukemia.
Pediatric blood & cancer - 1 Sept 2016
Abdelaziz Doaa H, Elhosseiny Noha M, Khaleel Sahar A, Sabry Nirmeen A, Attia Ahmed S, El-Sayed Manal H
Abstract excerpt
BACKGROUND: The aim of the present study is to determine the correlation of hepatitis C virus (HCV) infection and polymorphisms in different genes with toxicity of either methotrexate (MTX) or 6-mercaptopurine (6-MP) administered to children with acute lymphoblastic leukemia (ALL). PROCEDURE: One hundred children with low-risk ALL, who were treated according to the St. Jude Total therapy XV, were recruited. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.