Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose Homeostasis

9 May 2016

Abstract excerpt

The role of the Wnt signaling pathway in metabolic homeostasis has drawn our intensive attention, especially after the genome-wide association study discovery that certain polymorphisms of its key effector TCF7L2 are strongly associated with the susceptibility to type 2 diabetes. For a decade, great efforts have been made in determining the function of TCF7L2 in various metabolic organs, which have generated both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Pancreatic function and diabetes
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27159876
DOI: 10.1210/er.2015-1146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose HomeostasisPMID 27159876Read ↗

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspectiveSemantic proximity Read ↗

TCF7L2 and Glucose Metabolism: Time to Look Beyond the PancreasSemantic proximity Read ↗

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.Semantic proximity Read ↗

The role of transcription factor 7‐like 2 in metabolic disordersSemantic proximity Read ↗

The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes.Semantic proximity Read ↗

The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and FunctionSemantic proximity Read ↗

The Role of TCF7L2 in Type 2 Diabetes.Semantic proximity Read ↗

Wnt-signalling and the Metabolic SyndromeSemantic proximity Read ↗

The Role of Wnt3a/β-Catenin/TCF7L2 Pathway in Diabetes and Cardiorenal ComplicationsSemantic proximity Read ↗

The WNT signalling pathway and diabetes mellitusSemantic proximity Read ↗

TCF7L2 plays a complex role in human adipose progenitor biology which may contribute to genetic susceptibility to type 2 diabetesSemantic proximity Read ↗

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.