Article
Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at-onset of familial breast cancer.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Sept 2016
Lee Haiping, Geng Cuizhi, Cheng Meng, Lee Zheng, Guo Zhanjun
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are accumulated frequently in the mitochondrial displacement loop (D-loop) in various types of cancer, and their association with cancer risk and disease outcome has been extensively identified. We have identified specific risk-associated SNP for familial breast cancer patients previously. In this study, we investigated the association between age-at-onset and the SNPs in...
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