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Article

HLaffy: estimating peptide affinities for Class-1 HLA molecules by learning position-specific pair potentials.

Bioinformatics (Oxford, England) - 1 Aug 2016

Mukherjee Sumanta, Bhattacharyya Chiranjib, Chandra Nagasuma

Abstract excerpt

MOTIVATION: T-cell epitopes serve as molecular keys to initiate adaptive immune responses. Identification of T-cell epitopes is also a key step in rational vaccine design. Most available methods are driven by informatics and are critically dependent on experimentally obtained training data. Analysis of a training set from Immune Epitope Database (IEDB) for several alleles indicates that the sampling of the...

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PMID: 27153594
DOI: 10.1093/bioinformatics/btw156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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