Article
PepDist: a new framework for protein-peptide binding prediction based on learning peptide distance functions.
BMC bioinformatics - 20 Mar 2006
Hertz Tomer, Yanover Chen
Abstract excerpt
BACKGROUND: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples are MHC-peptide complexes in the immune system. Developing computational methods for protein-peptide binding prediction is therefore an important task with applications to vaccine and drug design. METHODS: Previous learning approaches...
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