Article
Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC alleles.
Protein science : a publication of the Protein Society - 1 Sept 2000
Schueler-Furman O, Altuvia Y, Sette A, Margalit H
Abstract excerpt
Specific binding of antigenic peptides to major histocompatibility complex (MHC) class I molecules is a prerequisite for their recognition by cytotoxic T-cells. Prediction of MHC-binding peptides must therefore be incorporated in any predictive algorithm attempting to identify immunodominant T-cell epitopes, based on the amino acid sequence of the protein antigen. Development of predictive algorithms based on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
