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Article

The c.657del5 variant in the NBN gene predisposes to pancreatic cancer.

Gene - 10 Aug 2016

Borecka Marianna, Zemankova Petra, Lhota Filip, Soukupova Jana, Kleiblova Petra, Vocka Michal, Soucek Pavel, Ticha Ivana, Kleibl Zdenek, Janatova Marketa

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is the sixth most frequent cancer type in the Czech Republic with a poor prognosis that could be improved by an early detection and subsequent surgical treatment combined with chemotherapy. Genetic factors play an important role in PDAC risk. We previously identified one PDAC patient harboring the Slavic founder deleterious mutation c.657del5 in the NBN gene, using a panel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27150568
DOI: 10.1016/j.gene.2016.04.056

Genes

NBN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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