The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients.

doi:10.3109/00365521.2016.1161066

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Article

The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients.

Scandinavian journal of gastroenterology - 1 Aug 2016

Vespasiani-Gentilucci Umberto, Gallo Paolo, Porcari Aldostefano, Carotti Simone, Galati Giovanni, Piccioni Livia, De Vincentis Antonio, Dell'Unto Chiara, Vorini Ferruccio, Morini Sergio, Riva Elisabetta, Picardi Antonio

Abstract excerpt

BACKGROUND AND AIMS: The patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 C > G single nucleotide polymorphism (SNP) has been associated with steatosis and fibrosis in previous NAFLD populations in which cirrhotic patients were very poorly represented. Since not all NAFLD with fibrosis evolve to cirrhosis, we investigated the specific risk of cirrhosis conferred in NAFLD patients by carrying this...

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PMID: 27150500
DOI: 10.3109/00365521.2016.1161066

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients.PMID 27150500Read ↗

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