A Common CD36 Variant Influences Endothelial Function and Response to Treatment with Phosphodiesterase 5 Inhibition.

doi:10.1210/jc.2016-1294

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Article

A Common CD36 Variant Influences Endothelial Function and Response to Treatment with Phosphodiesterase 5 Inhibition.

The Journal of clinical endocrinology and metabolism - 1 Jul 2016

Shibao Cyndya A, Celedonio Jorge E, Ramirez Claudia E, Love-Gregory Latisha, Arnold Amy C, Choi Leena, Okamoto Luis E, Gamboa Alfredo, Biaggioni Italo, Abumrad Naji N, Abumrad Nada A

Abstract excerpt

CONTEXT: The scavenger receptor CD36 influences the endothelial nitric oxide-cGMP pathway in vitro. Genetic variants that alter CD36 level are common in African Americans (AAs), a population at high risk of endothelial dysfunction. OBJECTIVE: To examine if the minor allele (G) of coding CD36 variant rs3211938 (G/T) which reduces CD36 level by approximately 50% influences endothelial function, insulin sensitivity...

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PMID: 27144937
DOI: 10.1210/jc.2016-1294
PMCID: PMC4929841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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