Article
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol.
Human molecular genetics - 1 Jun 2008
Love-Gregory Latisha, Sherva Richard, Sun Lingwei, Wasson Jon, Schappe Timothy, Doria Alessandro, Rao D C, Hunt Steven C, Klein Samuel, Neuman Rosalind J, Permutt M Alan, Abumrad Nada A
Abstract excerpt
A region along chromosome 7q was recently linked to components of the metabolic syndrome (MetS) in several genome-wide linkage studies. Within this region, the CD36 gene, which encodes a membrane receptor for long-chain fatty acids and lipoproteins, is a potentially important candidate. CD36 has been documented to play an important role in fatty acid metabolism in vivo and subsequently may be involved in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
