Article

ARPC5 Isoforms and Their Regulation by Calcium-Calmodulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells

2022-01-26

Abstract excerpt

Arp2/3-dependent formation of nuclear F-actin networks of different morphology and stability is observed in an increasing number of biological processes. In CD4 T cells, T cell receptor (TCR) signaling induces cytoplasmic and nuclear F-actin assembly via Arp2/3 to strengthen contacts to antigen presenting cells and to regulate gene expression, respectively. How Arp2/3 complex is regulated to mediate these distinct...

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Literature Corpus work: 13ff3a83-8b09-5d7c-95c9-3e36bbc0883d
DOI: 10.1101/2022.01.25.477674

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