Article
The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus.
PloS one - 1 Jan 2013
Koreishi Mayuko, Gniadek Thomas J, Yu Sidney, Masuda Junko, Honjo Yasuko, Satoh Ayano
Abstract excerpt
Golgins are coiled-coil proteins that play a key role in the regulation of Golgi architecture and function. Giantin, the largest golgin in mammals, forms a complex with p115, rab1, GM130, and soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs), thereby facilitating vesicle tethering and fusion processes around the Golgi apparatus. Treatment with the microtubule destabilizing drug...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
