Article
The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus.
PloS one - 1 Jan 2013
Koreishi Mayuko, Gniadek Thomas J, Yu Sidney, Masuda Junko, Honjo Yasuko, Satoh Ayano
Abstract excerpt
Golgins are coiled-coil proteins that play a key role in the regulation of Golgi architecture and function. Giantin, the largest golgin in mammals, forms a complex with p115, rab1, GM130, and soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs), thereby facilitating ves...
Topics
- Animals
- Autoantigens
- Cell Line
- Cell Separation
- DNA, Complementary
- Drosophila
- Flow Cytometry
- Glycosylation
- Golgi Apparatus
- Golgi Matrix Proteins
- HeLa Cells
- Humans
- Membrane Glycoproteins
- Membrane Proteins
- Nocodazole
- Phenotype
- Protein Binding
- Protein Structure, Tertiary