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Article

Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion.

Cell reports - 10 May 2016

Jiang Peng, Chen Chen, Liu Xiao-Bo, Pleasure David E, Liu Ying, Deng Wenbin

Abstract excerpt

Astrocytes, once considered passive support cells, are increasingly appreciated as dynamic regulators of neuronal development and function, in part via secreted factors. The extent to which they similarly regulate oligodendrocytes or proliferation and differentiation of oligodendrocyte progenitor cells (OPCs) is less understood. Here, we generated astrocytes from human pluripotent stem cells (hiPSC-Astros) and...

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Identifiers

PMID: 27134175
DOI: 10.1016/j.celrep.2016.04.011
PMCID: PMC4864503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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